Neural Therapy in a multidrug-resistant urinary tract infection in a cat: case report

Abstract

• Urinary tract infection is a frequent condition in companion animals, where several pathogens may be involved, among them, multidrug-resistant agents to antimicrobials, making their treatment difficult. In this context, adjuvant therapies can be indicated to assist in the treatment. Thus, the objective of this study was to report the antimicrobial action of a solution containing procaine hydrochloride associated with sodium bicarbonate, intravesically administered, in a male feline (domestic cat) with urinary tract infection due to multidrug-resistant microorganism. The cat with a history of urinary infection developed after urethrostomy was attended. The animal was receiving treatment with the antimicrobial amoxicillin with clavulanate, however, without positive clinical and laboratory response. After performing urine culture and antibiogram, where the microorganism Proteus mirabilis resistant to 18 classes of tested antimicrobials was isolated, an intravesical application of 2.0 mL of 0.7% procaine solution plus sodium bicarbonate was performed. After seven days of this application, a new urine culture and antibiogram were performed, which did not show any growth of microorganisms. It is concluded that the 0.7% procaine hydrochloride solution associated with intravesical sodium bicarbonate showed antimicrobial action against multi-resistant Proteus mirabilis, which causes urinary infection in a cat.